Why Does Trulance Cause Weight Gain


Why Does Trulance Cause Weight Gain?

Trulance (plecanatide) is a prescription medication used to treat chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). While it is generally well-tolerated, one of the reported side effects of Trulance is weight gain. In this article, we explore the reasons behind this occurrence and answer some common questions related to weight gain and Trulance.

1. How does Trulance work?
Trulance works increasing fluid secretion in the intestines, which helps to stimulate bowel movements and relieve constipation.

2. How common is weight gain with Trulance?
Weight gain is a reported side effect of Trulance, but it is not very common. In clinical trials, less than 2% of patients experienced weight gain.

3. Why does Trulance cause weight gain?
The exact mechanism behind Trulance-induced weight gain is not fully understood. However, it is believed that the increased fluid secretion caused Trulance can lead to water retention and, consequently, weight gain.

4. Is weight gain a serious side effect?
Weight gain associated with Trulance is generally not considered a serious side effect. However, it is important to monitor any significant weight changes and consult with your healthcare provider.

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5. Does everyone experience weight gain with Trulance?
No, weight gain is not experienced everyone using Trulance. It is a potential side effect that may affect a small percentage of individuals.

6. Can weight gain be prevented while taking Trulance?
Preventing weight gain while taking Trulance may be challenging, as it is a known side effect. However, maintaining a healthy lifestyle, including regular exercise and a balanced diet, may help minimize weight gain.

7. How much weight gain can be expected with Trulance?
The amount of weight gained with Trulance varies from person to person. In clinical trials, the average weight gain was less than one pound.

8. Can Trulance cause significant weight gain over time?
Significant weight gain over time as a result of Trulance is unlikely. However, individual experiences may vary, and it is essential to monitor any changes in weight and consult with your healthcare provider.

9. Is weight gain a reason to stop taking Trulance?
Weight gained while taking Trulance is generally not a reason to stop using the medication. However, if you experience significant or concerning weight gain, it is important to discuss this with your doctor.

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10. Can weight gain be a sign of an underlying condition?
Weight gain while taking Trulance is primarily attributed to water retention rather than an underlying condition. However, if you have concerns about any changes in your weight, it is always best to consult with your healthcare provider.

11. Will the weight gain subside over time?
Weight gain associated with Trulance is typically minimal and may subside over time. However, individual experiences may vary, and it is important to discuss any concerns with your doctor.

12. Does Trulance cause other gastrointestinal side effects?
Trulance may cause other gastrointestinal side effects such as diarrhea, abdominal pain, or bloating. If you experience any of these symptoms, it is important to contact your healthcare provider.

13. Are there alternative medications that do not cause weight gain?
There are alternative medications available for the treatment of chronic constipation and IBS-C. If weight gain is a concern for you, discuss possible alternatives with your healthcare provider.

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14. How can weight gain be managed while taking Trulance?
If you are concerned about weight gain while taking Trulance, it is important to maintain a healthy lifestyle. This includes regular exercise, a balanced diet, and staying hydrated. Monitoring your weight regularly and discussing any concerns with your healthcare provider is also advisable.

In conclusion, weight gain is a potential side effect of Trulance, although it is not very common. It is believed to be caused increased fluid secretion and subsequent water retention. While weight gain associated with Trulance is generally not considered serious, it is important to monitor any significant changes and consult with your healthcare provider.

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